HCSGD entry for PIP4K2A
1. General information
| Official gene symbol | PIP4K2A |
|---|---|
| Entrez ID | 5305 |
| Gene full name | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha |
| Other gene symbols | PI5P4KA PIP5K2A PIP5KII-alpha PIP5KIIA PIPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0016307 | Phosphatidylinositol phosphate kinase activity | IEA | molecular_function |
| GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity | NAS | molecular_function |
| GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity | IEA | molecular_function |
| GO:0035855 | Megakaryocyte development | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046854 | Phosphatidylinositol phosphorylation | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9637796170 | 0.0347563580 | 0.9999902473 | 0.3527386898 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1471881931 |
| GSE13712_SHEAR | Down | -0.1010012438 |
| GSE13712_STATIC | Down | -0.0780586660 |
| GSE19018 | Down | -0.6432400698 |
| GSE19899_A1 | Down | -0.3800964962 |
| GSE19899_A2 | Down | -0.6162774185 |
| PubMed_21979375_A1 | Down | -0.2344049660 |
| PubMed_21979375_A2 | Down | -0.6491726693 |
| GSE35957 | Down | -0.0674036429 |
| GSE36640 | Down | -0.7969052864 |
| GSE54402 | Up | 0.0400328096 |
| GSE9593 | Up | 0.3125908579 |
| GSE43922 | Down | -0.3649979997 |
| GSE24585 | Down | -0.4341367312 |
| GSE37065 | Down | -0.0444947950 |
| GSE28863_A1 | Up | 0.0927740748 |
| GSE28863_A2 | Up | 0.0230958420 |
| GSE28863_A3 | Down | -0.0289520086 |
| GSE28863_A4 | Up | 0.1982698163 |
| GSE48662 | Down | -0.4809391834 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-425-5p | MIMAT0003393 | MIRT016666 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023329 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023462 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027258 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041530 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
