HCSGD entry for PIN4
1. General information
| Official gene symbol | PIN4 |
|---|---|
| Entrez ID | 5303 |
| Gene full name | protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) |
| Other gene symbols | EPVH PAR14 PAR17 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003681 | Bent DNA binding | IDA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | IDA | molecular_function |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IDA IEA | cellular_component |
| GO:0005819 | Spindle | IDA IEA | cellular_component |
| GO:0006364 | RRNA processing | IMP | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0030684 | Preribosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6830240644 | 0.5650722047 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2456562214 |
| GSE13712_SHEAR | Down | -0.4576333497 |
| GSE13712_STATIC | Down | -0.3087356953 |
| GSE19018 | Up | 0.1513437848 |
| GSE19899_A1 | Up | 0.0570238038 |
| GSE19899_A2 | Down | -0.0059851392 |
| PubMed_21979375_A1 | Down | -0.1829852818 |
| PubMed_21979375_A2 | Down | -0.1029372320 |
| GSE35957 | Down | -0.0831928568 |
| GSE36640 | Up | 0.1186443277 |
| GSE54402 | Up | 0.1933152390 |
| GSE9593 | Down | -0.0788654822 |
| GSE43922 | Down | -0.1433463566 |
| GSE24585 | Up | 0.0980392017 |
| GSE37065 | Up | 0.0347358765 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1404948396 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040409 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040573 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
