HCSGD entry for PI4KA
1. General information
| Official gene symbol | PI4KA |
|---|---|
| Entrez ID | 5297 |
| Gene full name | phosphatidylinositol 4-kinase, catalytic, alpha |
| Other gene symbols | PI4K-ALPHA PIK4CA pi4K230 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004430 | 1-phosphatidylinositol 4-kinase activity | IBA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005798 | Golgi-associated vesicle | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IBA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016773 | Phosphotransferase activity, alcohol group as acceptor | IEA | molecular_function |
| GO:0030660 | Golgi-associated vesicle membrane | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046854 | Phosphatidylinositol phosphorylation | IEA | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2176060750 | 0.4084207059 | 0.8970987314 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2217112974 |
| GSE13712_SHEAR | Down | -0.0187949668 |
| GSE13712_STATIC | Up | 0.2001311645 |
| GSE19018 | Down | -0.1458201546 |
| GSE19899_A1 | Down | -0.4987107309 |
| GSE19899_A2 | Down | -0.3810125764 |
| PubMed_21979375_A1 | Up | 0.9322852632 |
| PubMed_21979375_A2 | Up | 0.4793285200 |
| GSE35957 | Down | -0.3745626954 |
| GSE36640 | Up | 0.6483149325 |
| GSE54402 | Up | 0.0609384506 |
| GSE9593 | Up | 0.2202198282 |
| GSE43922 | Down | -0.2975301840 |
| GSE24585 | Up | 0.3196231262 |
| GSE37065 | Down | -0.2602273997 |
| GSE28863_A1 | Up | 0.1995861063 |
| GSE28863_A2 | Down | -0.3814262495 |
| GSE28863_A3 | Up | 0.1548987491 |
| GSE28863_A4 | Up | 0.0299083117 |
| GSE48662 | Up | 0.1195160084 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041683 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048844 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
