HCSGD entry for ATP6V1E1
1. General information
| Official gene symbol | ATP6V1E1 |
|---|---|
| Entrez ID | 529 |
| Gene full name | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 |
| Other gene symbols | ATP6E ATP6E2 ATP6V1E P31 Vma4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005768 | Endosome | ISS | cellular_component |
| GO:0005829 | Cytosol | ISS TAS | cellular_component |
| GO:0005902 | Microvillus | IEA | cellular_component |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0008553 | Hydrogen-exporting ATPase activity, phosphorylative mechanism | IEA | molecular_function |
| GO:0015991 | ATP hydrolysis coupled proton transport | IEA | biological_process |
| GO:0015992 | Proton transport | TAS | biological_process |
| GO:0016324 | Apical plasma membrane | ISS | cellular_component |
| GO:0016469 | Proton-transporting two-sector ATPase complex | TAS | cellular_component |
| GO:0033178 | Proton-transporting two-sector ATPase complex, catalytic domain | IEA | cellular_component |
| GO:0033572 | Transferrin transport | TAS | biological_process |
| GO:0046961 | Proton-transporting ATPase activity, rotational mechanism | IEA | molecular_function |
| GO:0051117 | ATPase binding | IPI | molecular_function |
| GO:0051701 | Interaction with host | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0090382 | Phagosome maturation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0181086699 | 0.9665501045 | 0.3293975812 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.9982348315 |
| GSE13712_SHEAR | Down | -0.1053506850 |
| GSE13712_STATIC | Down | -0.0516550349 |
| GSE19018 | Down | -0.0130269077 |
| GSE19899_A1 | Up | 0.2995370125 |
| GSE19899_A2 | Up | 0.4482662331 |
| PubMed_21979375_A1 | Up | 0.3953679635 |
| PubMed_21979375_A2 | Up | 0.3553356886 |
| GSE35957 | Up | 0.3078230829 |
| GSE36640 | Up | 0.7527673890 |
| GSE54402 | Up | 0.4285876301 |
| GSE9593 | Up | 0.6697670309 |
| GSE43922 | Up | 0.0752120303 |
| GSE24585 | Up | 0.2413228428 |
| GSE37065 | Up | 0.3132262588 |
| GSE28863_A1 | Down | -0.3015549602 |
| GSE28863_A2 | Down | -0.0582358192 |
| GSE28863_A3 | Down | -0.5912483764 |
| GSE28863_A4 | Up | 0.2347991250 |
| GSE48662 | Up | 0.2269083718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023958 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031879 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038081 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040783 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046956 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
