HCSGD entry for SERPINB10
1. General information
| Official gene symbol | SERPINB10 |
|---|---|
| Entrez ID | 5273 |
| Gene full name | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| Other gene symbols | PI-10 PI10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IBA IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | IBA | biological_process |
| GO:0030162 | Regulation of proteolysis | IBA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1254823829 | 0.9341689487 | 0.7226858392 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0880012650 |
| GSE13712_SHEAR | Down | -0.0409051092 |
| GSE13712_STATIC | Up | 0.1923801366 |
| GSE19018 | Down | -0.0013728262 |
| GSE19899_A1 | Down | -0.1616200008 |
| GSE19899_A2 | Up | 0.2075601812 |
| PubMed_21979375_A1 | Up | 0.6336577250 |
| PubMed_21979375_A2 | Up | 0.1624490100 |
| GSE35957 | Down | -0.0569362328 |
| GSE36640 | Up | 0.3225439008 |
| GSE54402 | Up | 0.4911666888 |
| GSE9593 | Down | -0.1246542576 |
| GSE43922 | Up | 1.0326637361 |
| GSE24585 | Down | -0.0609433473 |
| GSE37065 | Up | 0.1116918343 |
| GSE28863_A1 | Down | -0.0136976821 |
| GSE28863_A2 | Up | 0.0238460283 |
| GSE28863_A3 | Up | 0.0044824258 |
| GSE28863_A4 | Up | 0.0469286975 |
| GSE48662 | Up | 0.0238503300 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017019 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
