HCSGD entry for SERPINB8

1. General information

Official gene symbolSERPINB8
Entrez ID5271
Gene full nameserpin peptidase inhibitor, clade B (ovalbumin), member 8
Other gene symbolsCAP2 PI8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0010951Negative regulation of endopeptidase activityIDAbiological_process
GO:0030162Regulation of proteolysisIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00375301470.53023998710.16409152821.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4639145687
GSE13712_SHEARUp0.4599561956
GSE13712_STATICUp0.2682426299
GSE19018Down-0.1177771541
GSE19899_A1Up1.1372563760
GSE19899_A2Up1.6035716214
PubMed_21979375_A1Up1.2972763160
PubMed_21979375_A2Up1.3776977808
GSE35957Up0.1008591078
GSE36640Up1.0267898078
GSE54402Up1.3880071926
GSE9593Down-0.0142077838
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.6349883399
GSE28863_A2Down-1.0828677321
GSE28863_A3Down-1.0615236994
GSE28863_A4Up0.2857176164
GSE48662Up0.0854289846

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.