HCSGD entry for SERPINB6
1. General information
| Official gene symbol | SERPINB6 |
|---|---|
| Entrez ID | 5269 |
| Gene full name | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| Other gene symbols | CAP DFNB91 MSTP057 PI-6 PI6 PTI SPI3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002020 | Protease binding | IPI | molecular_function |
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IBA IDA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | IBA IDA | biological_process |
| GO:0030162 | Regulation of proteolysis | IBA | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7541446336 | 0.5530540823 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0036897433 |
| GSE13712_SHEAR | Down | -0.1896484228 |
| GSE13712_STATIC | Down | -0.1434194705 |
| GSE19018 | Up | 0.2673262103 |
| GSE19899_A1 | Up | 0.0195263111 |
| GSE19899_A2 | Down | -0.1667773141 |
| PubMed_21979375_A1 | Up | 0.0222111565 |
| PubMed_21979375_A2 | Up | 0.0588130936 |
| GSE35957 | Down | -0.0375501556 |
| GSE36640 | Up | 0.0665770492 |
| GSE54402 | Down | -0.0373458133 |
| GSE9593 | Down | -0.0653276165 |
| GSE43922 | Down | -0.0909917145 |
| GSE24585 | Up | 0.6323758928 |
| GSE37065 | Down | -0.0944994165 |
| GSE28863_A1 | Up | 0.0316286979 |
| GSE28863_A2 | Up | 0.0166687678 |
| GSE28863_A3 | Down | -0.3561012247 |
| GSE28863_A4 | Down | -0.0624169178 |
| GSE48662 | Up | 0.1628852969 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002646 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002646 | Microarray | Functional MTI (Weak) | 15685193 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
