HCSGD entry for PHKA2
1. General information
| Official gene symbol | PHKA2 |
|---|---|
| Entrez ID | 5256 |
| Gene full name | phosphorylase kinase, alpha 2 (liver) |
| Other gene symbols | GSD9A PHK PYK PYKL XLG XLG2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004553 | Hydrolase activity, hydrolyzing O-glycosyl compounds | IEA | molecular_function |
| GO:0004689 | Phosphorylase kinase activity | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005964 | Phosphorylase kinase complex | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005980 | Glycogen catabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9884668592 | 0.0213643137 | 0.9999902473 | 0.2830045798 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0440031739 |
| GSE13712_SHEAR | Down | -0.2559714497 |
| GSE13712_STATIC | Down | -0.0691161223 |
| GSE19018 | Up | 0.1119871119 |
| GSE19899_A1 | Down | -0.0621744534 |
| GSE19899_A2 | Down | -0.5034660418 |
| PubMed_21979375_A1 | Down | -0.7697199084 |
| PubMed_21979375_A2 | Down | -0.4975190094 |
| GSE35957 | Down | -0.0998116578 |
| GSE36640 | Down | -0.6345341455 |
| GSE54402 | Down | -0.2849341753 |
| GSE9593 | Down | -0.3016205638 |
| GSE43922 | Down | -0.6227471889 |
| GSE24585 | Down | -0.8005843197 |
| GSE37065 | Down | -0.1740126694 |
| GSE28863_A1 | Up | 0.2668436388 |
| GSE28863_A2 | Up | 0.1410143761 |
| GSE28863_A3 | Down | -0.0660563143 |
| GSE28863_A4 | Up | 0.0116864035 |
| GSE48662 | Down | -0.2397961710 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030297 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045484 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
