HCSGD entry for PHF2
1. General information
| Official gene symbol | PHF2 |
|---|---|
| Entrez ID | 5253 |
| Gene full name | PHD finger protein 2 |
| Other gene symbols | CENP-35 GRC5 JHDM1E |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001889 | Liver development | TAS | biological_process |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0005506 | Iron ion binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006482 | Protein demethylation | IDA | biological_process |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0032452 | Histone demethylase activity | IDA | molecular_function |
| GO:0032454 | Histone demethylase activity (H3-K9 specific) | IDA | molecular_function |
| GO:0035064 | Methylated histone residue binding | IDA | molecular_function |
| GO:0051213 | Dioxygenase activity | IEA | molecular_function |
| GO:0061188 | Negative regulation of chromatin silencing at rDNA | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9098137875 | 0.1750778694 | 0.9999902473 | 0.8095529236 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0735738313 |
| GSE13712_SHEAR | Down | -0.0063492501 |
| GSE13712_STATIC | Up | 0.0437892994 |
| GSE19018 | Down | -0.1440247617 |
| GSE19899_A1 | Down | -0.3054847666 |
| GSE19899_A2 | Down | -0.5308248961 |
| PubMed_21979375_A1 | Down | -0.6566652129 |
| PubMed_21979375_A2 | Down | -0.3845959160 |
| GSE35957 | Down | -0.0984759238 |
| GSE36640 | Down | -0.1869837375 |
| GSE54402 | Down | -0.1225937970 |
| GSE9593 | Down | -0.1752183963 |
| GSE43922 | Down | -0.4448259150 |
| GSE24585 | Up | 0.4128491464 |
| GSE37065 | Up | 0.0135568104 |
| GSE28863_A1 | Up | 0.0881935514 |
| GSE28863_A2 | Up | 0.0535938365 |
| GSE28863_A3 | Up | 0.1577457650 |
| GSE28863_A4 | Up | 0.0974916772 |
| GSE48662 | Up | 0.3578376732 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
