HCSGD entry for PGM1
1. General information
| Official gene symbol | PGM1 |
|---|---|
| Entrez ID | 5236 |
| Gene full name | phosphoglucomutase 1 |
| Other gene symbols | CDG1T GSD14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004614 | Phosphoglucomutase activity | IDA TAS | molecular_function |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005829 | Cytosol | IBA TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005978 | Glycogen biosynthetic process | IBA TAS | biological_process |
| GO:0005980 | Glycogen catabolic process | TAS | biological_process |
| GO:0005992 | Trehalose biosynthetic process | IBA | biological_process |
| GO:0006006 | Glucose metabolic process | NAS TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0006096 | Glycolysis | TAS | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0019388 | Galactose catabolic process | IBA TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5010797348 | 0.0358485772 | 0.9999902473 | 0.3575484653 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6951290061 |
| GSE13712_SHEAR | Down | -0.2833208728 |
| GSE13712_STATIC | Up | 0.1494617315 |
| GSE19018 | Up | 0.8366146376 |
| GSE19899_A1 | Down | -0.5503685986 |
| GSE19899_A2 | Down | -0.3518746670 |
| PubMed_21979375_A1 | Down | -0.5412640450 |
| PubMed_21979375_A2 | Down | -0.2589899436 |
| GSE35957 | Up | 0.4155634109 |
| GSE36640 | Down | -1.1111391462 |
| GSE54402 | Up | 0.1928177584 |
| GSE9593 | Up | 0.1100563670 |
| GSE43922 | Down | -0.3361536674 |
| GSE24585 | Up | 0.3861057796 |
| GSE37065 | Up | 0.0058990772 |
| GSE28863_A1 | Down | -0.0161579906 |
| GSE28863_A2 | Up | 0.4249218334 |
| GSE28863_A3 | Down | -0.3826751488 |
| GSE28863_A4 | Down | -0.2098254651 |
| GSE48662 | Down | -0.4852525348 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Alpha-D-Glucose 1,6-Bisphosphate | DB02835 | EXPT01519 |
| Alpha-D-Glucose-1-Phosphate-6-Vanadate | DB04397 | EXPT03221 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002597 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002597 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005175 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052231 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 1756776 | Eight enzyme loci (G6PD, PGM1, PGM3, PepA, PGD, ADA, GLO1, and ME), proved to be informative in establishing unique allozyme genetic signatures for all of the cell strains established from the same species and from the same organ |
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