HCSGD entry for PFDN5

1. General information

Official gene symbolPFDN5
Entrez ID5204
Gene full nameprefoldin subunit 5
Other gene symbolsMM-1 MM1 PFD5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmTAScellular_component
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0006457Protein foldingIEA TASbiological_process
GO:0016272Prefoldin complexIEAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIMPbiological_process
GO:0051082Unfolded protein bindingIEAmolecular_function
GO:0051084'de novo' posttranslational protein foldingTASbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44458561600.43836868660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1885855911
GSE13712_SHEARDown-0.1239546289
GSE13712_STATICDown-0.1782931256
GSE19018Up0.0543679057
GSE19899_A1Down-0.1451837985
GSE19899_A2Down-0.0337723934
PubMed_21979375_A1Up0.3892896677
PubMed_21979375_A2Up0.0736156094
GSE35957Down-0.2401760091
GSE36640Up0.4043899520
GSE54402Up0.1432208186
GSE9593Up0.1473992918
GSE43922Up0.0101765129
GSE24585Up0.1787714634
GSE37065Down-0.2176498673
GSE28863_A1Up0.0529292995
GSE28863_A2Down-0.3579322771
GSE28863_A3Down-0.5531943126
GSE28863_A4Up0.2854264971
GSE48662Up0.1550467040

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028919MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.