HCSGD entry for PFDN4
1. General information
| Official gene symbol | PFDN4 |
|---|---|
| Entrez ID | 5203 |
| Gene full name | prefoldin subunit 4 |
| Other gene symbols | C1 PFD4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005829 | Cytosol | NAS | cellular_component |
| GO:0006457 | Protein folding | IEA TAS | biological_process |
| GO:0016272 | Prefoldin complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051087 | Chaperone binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4245885187 | 0.4903028608 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0975524516 |
| GSE13712_SHEAR | Up | 0.0315731425 |
| GSE13712_STATIC | Up | 0.0321698138 |
| GSE19018 | Down | -0.1501217066 |
| GSE19899_A1 | Up | 0.1390559635 |
| GSE19899_A2 | Up | 0.3245162472 |
| PubMed_21979375_A1 | Up | 0.9560136020 |
| PubMed_21979375_A2 | Up | 0.2206567462 |
| GSE35957 | Down | -0.0206070889 |
| GSE36640 | Up | 0.1723049058 |
| GSE54402 | Up | 0.3012834863 |
| GSE9593 | Down | -0.2437664963 |
| GSE43922 | Up | 0.1529805989 |
| GSE24585 | Down | -0.6231957805 |
| GSE37065 | Down | -0.0072653806 |
| GSE28863_A1 | Down | -0.0065591898 |
| GSE28863_A2 | Down | -0.0843648816 |
| GSE28863_A3 | Down | -0.1589922885 |
| GSE28863_A4 | Up | 0.0809636433 |
| GSE48662 | Down | -0.3980778618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020799 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
