HCSGD entry for ACP1
1. General information
| Official gene symbol | ACP1 |
|---|---|
| Entrez ID | 52 |
| Gene full name | acid phosphatase 1, soluble |
| Other gene symbols | HAAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003993 | Acid phosphatase activity | IEA | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0004726 | Non-membrane spanning protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0009898 | Cytoplasmic side of plasma membrane | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7252663045 | 0.2863502033 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2068819795 |
| GSE13712_SHEAR | Down | -0.0077065860 |
| GSE13712_STATIC | Up | 0.1014768684 |
| GSE19018 | Up | 0.0831382112 |
| GSE19899_A1 | Down | -0.1532389718 |
| GSE19899_A2 | Up | 0.0611653606 |
| PubMed_21979375_A1 | Up | 0.2013682336 |
| PubMed_21979375_A2 | Down | -0.3242821715 |
| GSE35957 | Down | -0.2309401094 |
| GSE36640 | Down | -0.1834083537 |
| GSE54402 | Up | 0.2396667681 |
| GSE9593 | Down | -0.0588694370 |
| GSE43922 | Down | -0.0133613751 |
| GSE24585 | Down | -0.3787091643 |
| GSE37065 | Down | -0.1736607476 |
| GSE28863_A1 | Up | 0.0572635840 |
| GSE28863_A2 | Up | 0.3143065406 |
| GSE28863_A3 | Up | 0.3452169582 |
| GSE28863_A4 | Down | -0.3013037343 |
| GSE48662 | Down | -0.1434308697 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Adenine | DB00173 | NUTR00012 | EXPT00520 |
| 4-Nitrophenyl Phosphate | DB04214 | EXPT00223 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-151a-3p | MIMAT0000757 | MIRT043619 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050258 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | NA | hsa-let-7a | 19939273 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 16673649 | OBJECTIVE: To study the activity of two enzymes, transmembrane reductase (TMR) and cytosolic low molecular weight protein tyrosine phosphatase (ACP1), in arterial hypertension (HT) in a sample of adults aged over 50 years |
| 16673649 | TMR (mmol/cell/h) and ACP1 (micromol/gHb/h) activity in red blood cells was determined by spectrophotometry |
| 16673649 | ACP1 activity, although higher in hypertensive patients, did not differ significantly from normotensive subjects (p = 0 |
| 728063 | An examination of the age-related patterns of decay of acid phosphatase (ACP1) in human red cells from individuals of different phenotypes |
| 728063 | A study has been made of the decay of acid phosphatase (ACP1) in the human red cell using red cell fractions of different mean ages prepared by density gradient centrifugation |
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