HCSGD entry for TMEM8B
1. General information
| Official gene symbol | TMEM8B |
|---|---|
| Entrez ID | 51754 |
| Gene full name | transmembrane protein 8B |
| Other gene symbols | C9orf127 NAG-5 NGX6 RP11-112J3.10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007160 | Cell-matrix adhesion | IMP | biological_process |
| GO:0007346 | Regulation of mitotic cell cycle | TAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0040008 | Regulation of growth | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7885058015 | 0.2927167167 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0440145312 |
| GSE13712_SHEAR | Down | -0.6662763796 |
| GSE13712_STATIC | Down | -0.2824112084 |
| GSE19018 | Up | 0.0802933937 |
| GSE19899_A1 | Down | -0.3152362635 |
| GSE19899_A2 | Up | 0.0458334752 |
| PubMed_21979375_A1 | Down | -0.5142613476 |
| PubMed_21979375_A2 | Up | 0.0842978097 |
| GSE35957 | Up | 0.0200561595 |
| GSE36640 | Up | 0.4218132044 |
| GSE54402 | Down | -0.1358961908 |
| GSE9593 | Up | 0.1300864615 |
| GSE43922 | Down | -0.1601330901 |
| GSE24585 | Up | 0.0943725106 |
| GSE37065 | Down | -0.1617235816 |
| GSE28863_A1 | Up | 0.1966808371 |
| GSE28863_A2 | Up | 0.1271157581 |
| GSE28863_A3 | Up | 0.0369761041 |
| GSE28863_A4 | Up | 0.0088876568 |
| GSE48662 | Up | 0.3552385797 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018101 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043252 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
