HCSGD entry for PDZK1
1. General information
| Official gene symbol | PDZK1 |
|---|---|
| Entrez ID | 5174 |
| Gene full name | PDZ domain containing 1 |
| Other gene symbols | CAP70 CLAMP NHERF-3 NHERF3 PDZD1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005124 | Scavenger receptor binding | IEA | molecular_function |
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006810 | Transport | IDA | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0015879 | Carnitine transport | IDA | biological_process |
| GO:0015893 | Drug transport | NAS | biological_process |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0030165 | PDZ domain binding | IPI | molecular_function |
| GO:0031526 | Brush border membrane | ISS | cellular_component |
| GO:0031528 | Microvillus membrane | IEA | cellular_component |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0034767 | Positive regulation of ion transmembrane transport | IDA | biological_process |
| GO:0044070 | Regulation of anion transport | ISS | biological_process |
| GO:0045121 | Membrane raft | IEA | cellular_component |
| GO:0090002 | Establishment of protein localization to plasma membrane | IEA | biological_process |
| GO:0090314 | Positive regulation of protein targeting to membrane | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0076756088 | 0.9795406444 | 0.2280695163 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4788949306 |
| GSE13712_SHEAR | Up | 0.2364297816 |
| GSE13712_STATIC | Down | -0.0759039103 |
| GSE19018 | Down | -0.3706414333 |
| GSE19899_A1 | Up | 0.4824711261 |
| GSE19899_A2 | Up | 0.6178171802 |
| PubMed_21979375_A1 | Up | 0.8821214314 |
| PubMed_21979375_A2 | Up | 1.2417974218 |
| GSE35957 | Down | -0.0719857374 |
| GSE36640 | Up | 1.2682184452 |
| GSE54402 | Up | 1.1447835478 |
| GSE9593 | Up | 0.0805359952 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.0233645334 |
| GSE28863_A2 | Up | 0.0764813847 |
| GSE28863_A3 | Up | 0.2750815700 |
| GSE28863_A4 | Up | 0.3431303889 |
| GSE48662 | Down | -0.1497930130 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019323 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021465 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
