HCSGD entry for CDK5RAP1
1. General information
| Official gene symbol | CDK5RAP1 |
|---|---|
| Entrez ID | 51654 |
| Gene full name | CDK5 regulatory subunit associated protein 1 |
| Other gene symbols | C20orf34 C42 CGI-05 HSPC167 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006400 | TRNA modification | IEA | biological_process |
| GO:0007420 | Brain development | NAS | biological_process |
| GO:0009451 | RNA modification | IEA | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | NAS | molecular_function |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0045664 | Regulation of neuron differentiation | NAS | biological_process |
| GO:0045736 | Negative regulation of cyclin-dependent protein serine/threonine kinase activity | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0639001520 | 0.7270674480 | 0.5450577447 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3757801787 |
| GSE13712_SHEAR | Down | -0.0356312080 |
| GSE13712_STATIC | Up | 0.2195676869 |
| GSE19018 | Down | -0.3116052265 |
| GSE19899_A1 | Up | 0.2556487113 |
| GSE19899_A2 | Up | 0.8475093273 |
| PubMed_21979375_A1 | Up | 1.1657377892 |
| PubMed_21979375_A2 | Up | 0.7941324121 |
| GSE35957 | Down | -0.5364705971 |
| GSE36640 | Down | -0.2379592201 |
| GSE54402 | Up | 0.2565474324 |
| GSE9593 | Down | -0.4232559711 |
| GSE43922 | Up | 0.4680219643 |
| GSE24585 | Up | 0.1188869507 |
| GSE37065 | Up | 0.0478075032 |
| GSE28863_A1 | Down | -0.0028058110 |
| GSE28863_A2 | Down | -0.2128959384 |
| GSE28863_A3 | Down | -0.3891787349 |
| GSE28863_A4 | Up | 0.1858728098 |
| GSE48662 | Down | -0.1042522848 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001473 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
