HCSGD entry for PTRH2
1. General information
| Official gene symbol | PTRH2 |
|---|---|
| Entrez ID | 51651 |
| Gene full name | peptidyl-tRNA hydrolase 2 |
| Other gene symbols | BIT1 PTH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004045 | Aminoacyl-tRNA hydrolase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA IMP | cellular_component |
| GO:0005829 | Cytosol | IMP | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0010629 | Negative regulation of gene expression | IMP | biological_process |
| GO:2000210 | Positive regulation of anoikis | IMP | biological_process |
| GO:2000811 | Negative regulation of anoikis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0010578891 | 0.9608669959 | 0.0876946541 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.4078705833 |
| GSE13712_SHEAR | Up | 0.8462211945 |
| GSE13712_STATIC | Up | 0.8631389831 |
| GSE19018 | Down | -0.5649563294 |
| GSE19899_A1 | Up | 1.1940491677 |
| GSE19899_A2 | Up | 1.5520600089 |
| PubMed_21979375_A1 | Up | 1.4440426083 |
| PubMed_21979375_A2 | Up | 1.2856811015 |
| GSE35957 | Up | 0.1899774370 |
| GSE36640 | Up | 0.7654012192 |
| GSE54402 | Up | 0.8346732385 |
| GSE9593 | Up | 0.2720570887 |
| GSE43922 | Up | 0.7808570271 |
| GSE24585 | Down | -0.2606388329 |
| GSE37065 | Up | 0.1355542014 |
| GSE28863_A1 | Down | -0.1893712568 |
| GSE28863_A2 | Down | -0.0348014902 |
| GSE28863_A3 | Down | -0.2722990498 |
| GSE28863_A4 | Up | 0.1138165002 |
| GSE48662 | Up | 0.1716440331 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028870 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041234 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041641 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
