HCSGD entry for KLF13
1. General information
| Official gene symbol | KLF13 |
|---|---|
| Entrez ID | 51621 |
| Gene full name | Kruppel-like factor 13 |
| Other gene symbols | BTEB3 FKLF2 NSLP1 RFLAT-1 RFLAT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IEA | biological_process |
| GO:0045647 | Negative regulation of erythrocyte differentiation | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1680997796 | 0.9621920976 | 0.8088764717 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1316548725 |
| GSE13712_SHEAR | Down | -0.1271559890 |
| GSE13712_STATIC | Down | -0.2144598801 |
| GSE19018 | Up | 0.1695391074 |
| GSE19899_A1 | Up | 0.1741401060 |
| GSE19899_A2 | Up | 0.3029156693 |
| PubMed_21979375_A1 | Up | 0.3708348543 |
| PubMed_21979375_A2 | Up | 0.4698193088 |
| GSE35957 | Up | 0.0829364048 |
| GSE36640 | Down | -0.1396337186 |
| GSE54402 | Up | 0.3099418423 |
| GSE9593 | Down | -0.0347641571 |
| GSE43922 | Up | 0.0688418594 |
| GSE24585 | Up | 0.0611900757 |
| GSE37065 | Up | 0.0586852952 |
| GSE28863_A1 | Up | 0.1832023965 |
| GSE28863_A2 | Up | 0.3085697473 |
| GSE28863_A3 | Up | 0.0350806760 |
| GSE28863_A4 | Up | 0.0498047754 |
| GSE48662 | Down | -0.0985390594 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-372-3p | MIMAT0000724 | MIRT000060 | Luciferase reporter assay//Microarray | Functional MTI | 19229866 |
| hsa-miR-302d-3p | MIMAT0000718 | MIRT000094 | Luciferase reporter assay//Microarray | Functional MTI | 19229866 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT003421 | Microarray//qRT-PCR//Western blot | Functional MTI | 19396866 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT003421 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT004972 | Luciferase reporter assay//qRT-PCR | Non-Functional MTI | 19524507 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT005339 | ELISA//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20589685 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT005676 | qRT-PCR | Non-Functional MTI (Weak) | 20589685 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018161 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-302d-3p | MIMAT0000718 | 1 | hsa-miR-302d | 19229866 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
