HCSGD entry for DPH5
1. General information
| Official gene symbol | DPH5 |
|---|---|
| Entrez ID | 51611 |
| Gene full name | diphthamide biosynthesis 5 |
| Other gene symbols | CGI-30 HSPC143 NPD015 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004164 | Diphthine synthase activity | NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0017183 | Peptidyl-diphthamide biosynthetic process from peptidyl-histidine | IEA NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9941535770 | 0.0051440257 | 0.9999902473 | 0.1459115302 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2902577058 |
| GSE13712_SHEAR | Down | -0.2740699776 |
| GSE13712_STATIC | Down | -0.0315847675 |
| GSE19018 | Up | 0.1771167704 |
| GSE19899_A1 | Down | -0.4395058219 |
| GSE19899_A2 | Down | -0.7812743149 |
| PubMed_21979375_A1 | Down | -0.9455250310 |
| PubMed_21979375_A2 | Down | -1.2744265153 |
| GSE35957 | Down | -0.6975055647 |
| GSE36640 | Down | -0.7199041478 |
| GSE54402 | Down | -0.4148899432 |
| GSE9593 | Down | -0.3333024301 |
| GSE43922 | Down | -0.4647278577 |
| GSE24585 | Down | -0.4611697457 |
| GSE37065 | Down | -0.3123196183 |
| GSE28863_A1 | Down | -0.1190542380 |
| GSE28863_A2 | Down | -0.0721809136 |
| GSE28863_A3 | Down | -0.5991915318 |
| GSE28863_A4 | Down | -0.0930420150 |
| GSE48662 | Down | -0.2692640670 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S-Adenosyl-L-Homocysteine | DB01752 | EXPT02842 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022425 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039181 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052597 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
