HCSGD entry for PDHA2
1. General information
| Official gene symbol | PDHA2 |
|---|---|
| Entrez ID | 5161 |
| Gene full name | pyruvate dehydrogenase (lipoamide) alpha 2 |
| Other gene symbols | PDHAL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004739 | Pyruvate dehydrogenase (acetyl-transferring) activity | IDA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006090 | Pyruvate metabolic process | IDA | biological_process |
| GO:0006096 | Glycolysis | IEA | biological_process |
| GO:0006099 | Tricarboxylic acid cycle | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5549110976 | 0.7876809620 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0149090928 |
| GSE13712_SHEAR | Down | -0.0648959151 |
| GSE13712_STATIC | Down | -0.0095751959 |
| GSE19018 | Up | 0.0119306610 |
| GSE19899_A1 | Up | 0.1721952332 |
| GSE19899_A2 | Up | 0.0661437231 |
| PubMed_21979375_A1 | Up | 0.1051405105 |
| PubMed_21979375_A2 | Up | 0.0197334276 |
| GSE35957 | Up | 0.2919866276 |
| GSE36640 | Down | -0.0392428753 |
| GSE54402 | Down | -0.0294655797 |
| GSE9593 | Down | -0.0516510461 |
| GSE43922 | Up | 0.1307599259 |
| GSE24585 | Down | -0.1701712514 |
| GSE37065 | Up | 0.0887190766 |
| GSE28863_A1 | Up | 0.0019717698 |
| GSE28863_A2 | Up | 0.0840552142 |
| GSE28863_A3 | Up | 0.0158111533 |
| GSE28863_A4 | Up | 0.0968002288 |
| GSE48662 | Down | -0.2573658015 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT000170 | Quantitative proteomic approach | Functional MTI (Weak) | 19253296 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029395 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
