HCSGD entry for ATP6V1H


1. General information

Official gene symbolATP6V1H
Entrez ID51606
Gene full nameATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
Other gene symbolsMSTP042 NBP1 SFD SFDalpha SFDbeta VMA13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000221Vacuolar proton-transporting V-type ATPase, V1 domainIEA NAScellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006200ATP catabolic processNASbiological_process
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006897EndocytosisIDAbiological_process
GO:0007035Vacuolar acidificationNASbiological_process
GO:0008152Metabolic processNASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0015991ATP hydrolysis coupled proton transportIEA NASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016887ATPase activityNASmolecular_function
GO:0030234Enzyme regulator activityNASmolecular_function
GO:0033572Transferrin transportTASbiological_process
GO:0046961Proton-transporting ATPase activity, rotational mechanismIEAmolecular_function
GO:0050690Regulation of defense response to virus by virusTASbiological_process
GO:0050790Regulation of catalytic activityNASbiological_process
GO:0051701Interaction with hostTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12007819990.96355698870.70892284751.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2166875873
GSE13712_SHEARDown-0.0548454016
GSE13712_STATICUp0.1107848384
GSE19018Up0.1696517815
GSE19899_A1Up0.2884868419
GSE19899_A2Up0.1716711465
PubMed_21979375_A1Up0.2655908713
PubMed_21979375_A2Up0.3255126754
GSE35957Up0.1727868552
GSE36640Up0.0764661887
GSE54402Up0.0635553182
GSE9593Up0.2966998205
GSE43922Up0.2633666770
GSE24585Up0.3491185719
GSE37065Up0.1311149684
GSE28863_A1Down-0.2251135318
GSE28863_A2Up0.0174153900
GSE28863_A3Down-0.2210191625
GSE28863_A4Up0.0582345006
GSE48662Down-0.0803688736

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020893ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.