HCSGD entry for TRIM33
1. General information
| Official gene symbol | TRIM33 |
|---|---|
| Entrez ID | 51592 |
| Gene full name | tripartite motif containing 33 |
| Other gene symbols | ECTO PTC7 RFG7 TF1G TIF1G TIF1GAMMA TIFGAMMA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0017015 | Regulation of transforming growth factor beta receptor signaling pathway | IDA | biological_process |
| GO:0030514 | Negative regulation of BMP signaling pathway | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0070410 | Co-SMAD binding | IPI | molecular_function |
| GO:0070412 | R-SMAD binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1459526956 | 0.8386996163 | 0.7661474786 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2136065494 |
| GSE13712_SHEAR | Down | -0.0925895366 |
| GSE13712_STATIC | Down | -0.0848881681 |
| GSE19018 | Down | -0.0733523506 |
| GSE19899_A1 | Up | 0.1121850125 |
| GSE19899_A2 | Up | 0.4323651694 |
| PubMed_21979375_A1 | Up | 0.1554349292 |
| PubMed_21979375_A2 | Up | 0.6460205289 |
| GSE35957 | Down | -0.3738207931 |
| GSE36640 | Down | -0.1804028857 |
| GSE54402 | Up | 0.2287622362 |
| GSE9593 | Down | -0.2699660136 |
| GSE43922 | Up | 0.2622590465 |
| GSE24585 | Up | 0.1138877954 |
| GSE37065 | Up | 0.1330455246 |
| GSE28863_A1 | Up | 0.3056711286 |
| GSE28863_A2 | Up | 0.6789159911 |
| GSE28863_A3 | Down | -0.3296791138 |
| GSE28863_A4 | Down | -0.2541834697 |
| GSE48662 | Up | 0.1433402454 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030846 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031198 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037486 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-3p | MIMAT0004481 | MIRT039002 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
