HCSGD entry for ANAPC11

1. General information

Official gene symbolANAPC11
Entrez ID51529
Gene full nameanaphase promoting complex subunit 11
Other gene symbolsAPC11 Apc11p
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0004842Ubiquitin-protein ligase activityIDA IEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005680Anaphase-promoting complexIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007067MitosisTASbiological_process
GO:0007094Mitotic spindle assembly checkpointTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0031145Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic processTASbiological_process
GO:0051436Negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051437Positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0051439Regulation of ubiquitin-protein ligase activity involved in mitotic cell cycleTASbiological_process
GO:0070979Protein K11-linked ubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82462737740.23085432160.99999024730.9249987213

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1007916412
GSE13712_SHEARUp0.1252886816
GSE13712_STATICUp0.1393471662
GSE19018Up0.1878519387
GSE19899_A1Down-0.2164063962
GSE19899_A2Up0.1282473301
PubMed_21979375_A1Up0.6108090453
PubMed_21979375_A2Down-0.0547636309
GSE35957Down-0.2129384476
GSE36640Down-0.2096948060
GSE54402Up0.0905956216
GSE9593Down-0.1902497159
GSE43922Up0.0447135415
GSE24585Up0.0960237228
GSE37065Down-0.1134358445
GSE28863_A1Down-0.5870472673
GSE28863_A2Down-0.5374221000
GSE28863_A3Up0.1880440186
GSE28863_A4Down-0.0663380340
GSE48662Down-0.0266957466

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-100-5pMIMAT0000098MIRT048482CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.