HCSGD entry for HSD17B7
1. General information
| Official gene symbol | HSD17B7 |
|---|---|
| Entrez ID | 51478 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 7 |
| Other gene symbols | PRAP SDR37C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000253 | 3-keto sterol reductase activity | IEA | molecular_function |
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | IEA | molecular_function |
| GO:0005148 | Prolactin receptor binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006695 | Cholesterol biosynthetic process | TAS | biological_process |
| GO:0006703 | Estrogen biosynthetic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9198497701 | 0.1222846092 | 0.9999902473 | 0.6709721076 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3853923365 |
| GSE13712_SHEAR | Down | -0.5361061713 |
| GSE13712_STATIC | Down | -0.2981053831 |
| GSE19018 | Down | -0.1241527883 |
| GSE19899_A1 | Up | 0.0090468150 |
| GSE19899_A2 | Up | 0.1988847811 |
| PubMed_21979375_A1 | Down | -1.9285509078 |
| PubMed_21979375_A2 | Down | -0.0014084301 |
| GSE35957 | Down | -0.3201998782 |
| GSE36640 | Up | 0.4524614919 |
| GSE54402 | Down | -0.0724945204 |
| GSE9593 | Down | -0.5147540934 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.1745950309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018884 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020937 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
