HCSGD entry for ISYNA1
1. General information
| Official gene symbol | ISYNA1 |
|---|---|
| Entrez ID | 51477 |
| Gene full name | inositol-3-phosphate synthase 1 |
| Other gene symbols | INO1 INOS IPS IPS 1 IPS-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004512 | Inositol-3-phosphate synthase activity | IEA TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006021 | Inositol biosynthetic process | IEA | biological_process |
| GO:0008654 | Phospholipid biosynthetic process | IEA | biological_process |
| GO:0043647 | Inositol phosphate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4775430949 | 0.6572865811 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0706516912 |
| GSE13712_SHEAR | Down | -0.5517745630 |
| GSE13712_STATIC | Down | -0.2359864922 |
| GSE19018 | Up | 0.0699209462 |
| GSE19899_A1 | Down | -0.1437528266 |
| GSE19899_A2 | Up | 0.2565355994 |
| PubMed_21979375_A1 | Up | 0.0795284425 |
| PubMed_21979375_A2 | Up | 0.5011028161 |
| GSE35957 | Down | -0.0237510587 |
| GSE36640 | Up | 0.0066176476 |
| GSE54402 | Down | -0.0612318926 |
| GSE9593 | Down | -0.0825665788 |
| GSE43922 | Up | 0.0534137374 |
| GSE24585 | Up | 0.2969615771 |
| GSE37065 | Down | -0.0345477091 |
| GSE28863_A1 | Up | 0.0042606341 |
| GSE28863_A2 | Down | -0.2589043460 |
| GSE28863_A3 | Up | 0.2737651397 |
| GSE28863_A4 | Up | 0.1145264124 |
| GSE48662 | Up | 0.5100155683 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate | DB01840 | EXPT01100 |
| Glycerol | DB04077 | EXPT01027 |
| 2-Deoxy-Glucitol-6-Phosphate | DB04516 | EXPT01174 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004188 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-320a | MIMAT0000510 | MIRT044693 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
