HCSGD entry for PDE6D
1. General information
| Official gene symbol | PDE6D |
|---|---|
| Entrez ID | 5147 |
| Gene full name | phosphodiesterase 6D, cGMP-specific, rod, delta |
| Other gene symbols | PDED |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | IEA | molecular_function |
| GO:0005095 | GTPase inhibitor activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0017137 | Rab GTPase binding | IPI | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
| GO:0033124 | Regulation of GTP catabolic process | IEA ISS | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | ISS | biological_process |
| GO:0050790 | Regulation of catalytic activity | ISS | biological_process |
| GO:0050896 | Response to stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4992649557 | 0.3644104859 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2804065497 |
| GSE13712_SHEAR | Up | 0.0083265500 |
| GSE13712_STATIC | Up | 0.0787058581 |
| GSE19018 | Up | 0.5827057879 |
| GSE19899_A1 | Up | 0.0856543302 |
| GSE19899_A2 | Down | -0.2801170672 |
| PubMed_21979375_A1 | Down | -0.2616080886 |
| PubMed_21979375_A2 | Down | -0.3626835392 |
| GSE35957 | Down | -0.0594165899 |
| GSE36640 | Down | -0.3083677695 |
| GSE54402 | Up | 0.1192824892 |
| GSE9593 | Up | 0.0267679150 |
| GSE43922 | Down | -0.0031985856 |
| GSE24585 | Up | 0.4406647032 |
| GSE37065 | Up | 0.0606846345 |
| GSE28863_A1 | Down | -0.1907604751 |
| GSE28863_A2 | Up | 0.0605585878 |
| GSE28863_A3 | Down | -0.1029906512 |
| GSE28863_A4 | Down | -0.2365582665 |
| GSE48662 | Down | -0.4344141692 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048274 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
