HCSGD entry for LCMT1
1. General information
| Official gene symbol | LCMT1 |
|---|---|
| Entrez ID | 51451 |
| Gene full name | leucine carboxyl methyltransferase 1 |
| Other gene symbols | LCMT PPMT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003880 | Protein C-terminal carboxyl O-methyltransferase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006479 | Protein methylation | IMP | biological_process |
| GO:0006481 | C-terminal protein methylation | IDA | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | TAS | molecular_function |
| GO:0031333 | Negative regulation of protein complex assembly | IMP | biological_process |
| GO:0042981 | Regulation of apoptotic process | IMP | biological_process |
| GO:0090266 | Regulation of mitotic cell cycle spindle assembly checkpoint | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8603614604 | 0.4000628851 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2860549291 |
| GSE13712_SHEAR | Down | -0.3367257274 |
| GSE13712_STATIC | Down | -0.1714307597 |
| GSE19018 | Up | 0.1862515983 |
| GSE19899_A1 | Down | -0.3817863274 |
| GSE19899_A2 | Down | -0.1782894111 |
| PubMed_21979375_A1 | Up | 0.1781323422 |
| PubMed_21979375_A2 | Up | 0.0086711334 |
| GSE35957 | Down | -0.2641740780 |
| GSE36640 | Up | 0.1087278828 |
| GSE54402 | Down | -0.0572674364 |
| GSE9593 | Up | 0.1950213989 |
| GSE43922 | Down | -0.0128692432 |
| GSE24585 | Down | -0.0278550804 |
| GSE37065 | Down | -0.0881491422 |
| GSE28863_A1 | Up | 0.0313535820 |
| GSE28863_A2 | Down | -0.0782115924 |
| GSE28863_A3 | Down | -0.0213148522 |
| GSE28863_A4 | Up | 0.0205946967 |
| GSE48662 | Down | -0.0793396647 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Leucine | DB00149 | NUTR00033 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
