HCSGD entry for RNF138
1. General information
| Official gene symbol | RNF138 |
|---|---|
| Entrez ID | 51444 |
| Gene full name | ring finger protein 138, E3 ubiquitin protein ligase |
| Other gene symbols | HSD-4 NARF STRIN hNARF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9452017135 | 0.0039387599 | 0.9999902473 | 0.1277365314 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5080376398 |
| GSE13712_SHEAR | Down | -0.0128001783 |
| GSE13712_STATIC | Up | 0.3935920287 |
| GSE19018 | Down | -0.7563902548 |
| GSE19899_A1 | Down | -0.6398646309 |
| GSE19899_A2 | Down | -0.8180788504 |
| PubMed_21979375_A1 | Up | 0.5621053889 |
| PubMed_21979375_A2 | Down | -0.7751543848 |
| GSE35957 | Down | -0.6485894782 |
| GSE36640 | Down | -2.1132155853 |
| GSE54402 | Up | 0.4907531963 |
| GSE9593 | Down | -0.7309431981 |
| GSE43922 | Up | 0.0025767794 |
| GSE24585 | Down | -0.2644246562 |
| GSE37065 | Up | 0.2385389290 |
| GSE28863_A1 | Up | 0.2083065668 |
| GSE28863_A2 | Down | -0.5323256005 |
| GSE28863_A3 | Down | -0.2786854873 |
| GSE28863_A4 | Down | -0.3145550122 |
| GSE48662 | Down | -0.6500644289 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002787 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002787 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-421 | MIMAT0003339 | MIRT016112 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
