HCSGD entry for BIN2
1. General information
| Official gene symbol | BIN2 |
|---|---|
| Entrez ID | 51411 |
| Gene full name | bridging integrator 2 |
| Other gene symbols | BRAP-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001891 | Phagocytic cup | IDA | cellular_component |
| GO:0002102 | Podosome | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005543 | Phospholipid binding | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0006911 | Phagocytosis, engulfment | IMP | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0060326 | Cell chemotaxis | IMP | biological_process |
| GO:0071800 | Podosome assembly | IMP | biological_process |
| GO:0097320 | Membrane tubulation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6830096615 | 0.8782160100 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0251627767 |
| GSE13712_SHEAR | Down | -0.1263839901 |
| GSE13712_STATIC | Up | 0.1169714407 |
| GSE19018 | Up | 0.1800642155 |
| GSE19899_A1 | Up | 0.0072171587 |
| GSE19899_A2 | Up | 0.0688474769 |
| PubMed_21979375_A1 | Up | 0.3569843725 |
| PubMed_21979375_A2 | Down | -0.0597970867 |
| GSE35957 | Up | 0.1021956554 |
| GSE36640 | Up | 0.0046995646 |
| GSE54402 | Up | 0.1218762596 |
| GSE9593 | Up | 0.0047714074 |
| GSE43922 | Up | 0.0007429339 |
| GSE24585 | Down | -0.0166147684 |
| GSE37065 | Down | -0.0397101231 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0713375010 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
