HCSGD entry for ATP5E
1. General information
| Official gene symbol | ATP5E |
|---|---|
| Entrez ID | 514 |
| Gene full name | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit |
| Other gene symbols | ATPE MC5DN3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000275 | Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) | IEA | cellular_component |
| GO:0005753 | Mitochondrial proton-transporting ATP synthase complex | IDA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0016887 | ATPase activity | IDA | molecular_function |
| GO:0022857 | Transmembrane transporter activity | IC | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0042776 | Mitochondrial ATP synthesis coupled proton transport | IC TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046933 | Proton-transporting ATP synthase activity, rotational mechanism | IEA | molecular_function |
| GO:0046961 | Proton-transporting ATPase activity, rotational mechanism | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3189733635 | 0.7137126667 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0404423557 |
| GSE13712_SHEAR | Down | -0.0610508979 |
| GSE13712_STATIC | Down | -0.0010943916 |
| GSE19018 | Up | 0.0540336790 |
| GSE19899_A1 | Up | 0.0339372697 |
| GSE19899_A2 | Down | -0.0564834627 |
| PubMed_21979375_A1 | Up | 0.3110421673 |
| PubMed_21979375_A2 | Down | -0.2671761564 |
| GSE35957 | Down | -0.0649075104 |
| GSE36640 | Down | -0.0868897153 |
| GSE54402 | Up | 0.1629829484 |
| GSE9593 | Up | 0.3612623396 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.2718827650 |
| GSE28863_A2 | Up | 0.5869380162 |
| GSE28863_A3 | Up | 0.2794741741 |
| GSE28863_A4 | Down | -0.2046385467 |
| GSE48662 | Up | 0.0041627062 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039871 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048667 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3181 | MIMAT0015061 | MIRT052805 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
