HCSGD entry for CRLF3


1. General information

Official gene symbolCRLF3
Entrez ID51379
Gene full namecytokine receptor-like factor 3
Other gene symbolsCREME-9 CREME9 CRLM9 CYTOR4 FRWS p48.2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIMPbiological_process
GO:0005737CytoplasmIDAcellular_component
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046427Positive regulation of JAK-STAT cascadeIDAbiological_process
GO:0071158Positive regulation of cell cycle arrestIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01120794420.72740221500.26782849361.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2252935420
GSE13712_SHEARUp0.2825679423
GSE13712_STATICUp0.1459970777
GSE19018Up0.0276981942
GSE19899_A1Up1.5283327518
GSE19899_A2Up1.1609497514
PubMed_21979375_A1Up1.6643707711
PubMed_21979375_A2Up1.0345242773
GSE35957Down-0.3207266020
GSE36640Down-0.3949875518
GSE54402Up0.9008601058
GSE9593Down-0.0600562610
GSE43922Up0.6763820159
GSE24585Down-0.2757677027
GSE37065Down-0.1624580558
GSE28863_A1Down-0.2103016870
GSE28863_A2Down-0.1987659191
GSE28863_A3Up0.1395958308
GSE28863_A4Up0.4269775655
GSE48662Up0.0457410232

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019999MicroarrayFunctional MTI (Weak)20215506
hsa-miR-215-5pMIMAT0000272MIRT024952MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026882MicroarrayFunctional MTI (Weak)19074876
hsa-miR-671-5pMIMAT0003880MIRT039257CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.