HCSGD entry for NGRN


1. General information

Official gene symbolNGRN
Entrez ID51335
Gene full nameneugrin, neurite outgrowth associated
Other gene symbolsDSC92
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005634NucleusNAScellular_component
GO:0030182Neuron differentiationNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.27789084000.03912267010.97513935480.3728393775

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4112902193
GSE13712_SHEARUp0.4165758342
GSE13712_STATICUp0.2218591373
GSE19018Up0.2345262673
GSE19899_A1Down-0.0409555097
GSE19899_A2Up0.0953735329
PubMed_21979375_A1Down-0.1070873387
PubMed_21979375_A2Down-0.1724567165
GSE35957Up0.3974369307
GSE36640Up0.4157855791
GSE54402Down-0.0999619812
GSE9593Up0.3163105970
GSE43922Down-0.0076080234
GSE24585Up0.2778509740
GSE37065Down-0.0593772117
GSE28863_A1Down-1.3352205204
GSE28863_A2Down-2.1101618236
GSE28863_A3Down-0.9360703090
GSE28863_A4Down-0.1257254449
GSE48662Up0.2267596810

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-342-3pMIMAT0000753MIRT043687CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045692CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046683CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

18836295Recently, some studies indicated that coupling special ligand like NGR (N: asparagine, G: glycine, R: arginine) peptide targeting to tumor blood vessels with delivery system can enhance the efficacy of gene transfection
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