HCSGD entry for TNFRSF12A
1. General information
| Official gene symbol | TNFRSF12A |
|---|---|
| Entrez ID | 51330 |
| Gene full name | tumor necrosis factor receptor superfamily, member 12A |
| Other gene symbols | CD266 FN14 TWEAKR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0006931 | Substrate-dependent cell migration, cell attachment to substrate | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0045773 | Positive regulation of axon extension | IEA | biological_process |
| GO:2001238 | Positive regulation of extrinsic apoptotic signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0470451541 | 0.2942196231 | 0.4802644436 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2244975634 |
| GSE13712_SHEAR | Up | 1.9447926333 |
| GSE13712_STATIC | Up | 0.8101504625 |
| GSE19018 | Down | -1.1045182657 |
| GSE19899_A1 | Down | -0.1134966148 |
| GSE19899_A2 | Up | 0.0504660231 |
| PubMed_21979375_A1 | Up | 0.5914503330 |
| PubMed_21979375_A2 | Down | -0.1297483481 |
| GSE35957 | Down | -0.0606567092 |
| GSE36640 | Down | -0.0944430324 |
| GSE54402 | Up | 0.5736093910 |
| GSE9593 | Up | 0.5178303067 |
| GSE43922 | Up | 0.2638427030 |
| GSE24585 | Up | 0.1316160896 |
| GSE37065 | Up | 0.0247179237 |
| GSE28863_A1 | Down | -0.4858494518 |
| GSE28863_A2 | Up | 0.0409619099 |
| GSE28863_A3 | Down | -0.2485490362 |
| GSE28863_A4 | Up | 0.1287686743 |
| GSE48662 | Down | -0.4389912971 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022342 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031460 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042306 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
