HCSGD entry for PDCD1
1. General information
| Official gene symbol | PDCD1 |
|---|---|
| Entrez ID | 5133 |
| Gene full name | programmed cell death 1 |
| Other gene symbols | CD279 PD-1 PD1 SLEB2 hPD-1 hPD-l |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004871 | Signal transducer activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006959 | Humoral immune response | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031295 | T cell costimulation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7648429011 | 0.7028760913 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2141931956 |
| GSE13712_SHEAR | Up | 0.2620010732 |
| GSE13712_STATIC | Up | 0.0450078118 |
| GSE19018 | Down | -0.0522667987 |
| GSE19899_A1 | Down | -0.1801386299 |
| GSE19899_A2 | Up | 0.0548125485 |
| PubMed_21979375_A1 | Down | -0.1446040941 |
| PubMed_21979375_A2 | Down | -0.0904052823 |
| GSE35957 | Up | 0.3163405743 |
| GSE36640 | Up | 0.0642474605 |
| GSE54402 | Up | 0.0182964060 |
| GSE9593 | Up | 0.0592793521 |
| GSE43922 | Up | 0.0639989968 |
| GSE24585 | Down | -0.0094275206 |
| GSE37065 | Down | -0.0983972715 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.0003675738 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22829758 | These include COL4A3, CFLAR, GULP1, PDCD1, CASP10, PAX3, BOK, HSPD1, PITX2, and PML |
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