HCSGD entry for CYP39A1
1. General information
| Official gene symbol | CYP39A1 |
|---|---|
| Entrez ID | 51302 |
| Gene full name | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006699 | Bile acid biosynthetic process | IDA TAS | biological_process |
| GO:0006707 | Cholesterol catabolic process | IEA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0007586 | Digestion | TAS | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0008387 | Steroid 7-alpha-hydroxylase activity | IEA | molecular_function |
| GO:0008396 | Oxysterol 7-alpha-hydroxylase activity | IDA | molecular_function |
| GO:0016125 | Sterol metabolic process | TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0030573 | Bile acid catabolic process | IEA | biological_process |
| GO:0033782 | 24-hydroxycholesterol 7alpha-hydroxylase activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4409519851 | 0.9157974165 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0153941093 |
| GSE13712_SHEAR | Down | -0.0640787112 |
| GSE13712_STATIC | Down | -0.1157718407 |
| GSE19018 | Down | -0.0863030439 |
| GSE19899_A1 | Up | 0.1923560896 |
| GSE19899_A2 | Up | 0.2044859865 |
| PubMed_21979375_A1 | Up | 0.1385618381 |
| PubMed_21979375_A2 | Up | 0.1158579884 |
| GSE35957 | Up | 0.0090870870 |
| GSE36640 | Up | 0.1548656559 |
| GSE54402 | Up | 0.0804885680 |
| GSE9593 | Up | 0.2809725188 |
| GSE43922 | Up | 0.1045517358 |
| GSE24585 | Down | -0.2878731533 |
| GSE37065 | Up | 0.0491183624 |
| GSE28863_A1 | Up | 0.0583016533 |
| GSE28863_A2 | Up | 0.2253709481 |
| GSE28863_A3 | Up | 0.1203414720 |
| GSE28863_A4 | Up | 0.0075629002 |
| GSE48662 | Down | -0.0535941233 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018738 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021447 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
