HCSGD entry for ECSIT
1. General information
| Official gene symbol | ECSIT |
|---|---|
| Entrez ID | 51295 |
| Gene full name | ECSIT signalling integrator |
| Other gene symbols | SITPEC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001707 | Mesoderm formation | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0016651 | Oxidoreductase activity, acting on NAD(P)H | IDA | molecular_function |
| GO:0030509 | BMP signaling pathway | IEA | biological_process |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0051341 | Regulation of oxidoreductase activity | IDA | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7451177805 | 0.2150483910 | 0.9999902473 | 0.8949073043 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0785211466 |
| GSE13712_SHEAR | Down | -0.2292889474 |
| GSE13712_STATIC | Down | -0.5153958452 |
| GSE19018 | Up | 0.1366666848 |
| GSE19899_A1 | Up | 0.0447574522 |
| GSE19899_A2 | Down | -0.4423980203 |
| PubMed_21979375_A1 | Up | 0.3594183153 |
| PubMed_21979375_A2 | Up | 0.3177443604 |
| GSE35957 | Down | -0.4375337350 |
| GSE36640 | Down | -0.5674491683 |
| GSE54402 | Up | 0.0297996348 |
| GSE9593 | Down | -0.3856793011 |
| GSE43922 | Up | 0.0651340938 |
| GSE24585 | Down | -0.3247336817 |
| GSE37065 | Down | -0.2099003958 |
| GSE28863_A1 | Up | 0.2051943411 |
| GSE28863_A2 | Up | 0.0114297398 |
| GSE28863_A3 | Up | 0.1781387117 |
| GSE28863_A4 | Down | -0.0582687363 |
| GSE48662 | Up | 0.1519378298 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-3p | MIMAT0004612 | MIRT038614 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
