HCSGD entry for GMPR2
1. General information
| Official gene symbol | GMPR2 |
|---|---|
| Entrez ID | 51292 |
| Gene full name | guanosine monophosphate reductase 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0003920 | GMP reductase activity | IDA IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006144 | Purine nucleobase metabolic process | TAS | biological_process |
| GO:0009117 | Nucleotide metabolic process | IEA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0043101 | Purine-containing compound salvage | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046037 | GMP metabolic process | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
| GO:0055114 | Oxidation-reduction process | IEA | biological_process |
| GO:1902560 | GMP reductase complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9082146309 | 0.0793851297 | 0.9999902473 | 0.5323601019 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3143458843 |
| GSE13712_SHEAR | Down | -0.0785384504 |
| GSE13712_STATIC | Down | -0.1056756071 |
| GSE19018 | Up | 0.1771127471 |
| GSE19899_A1 | Down | -0.2505985739 |
| GSE19899_A2 | Down | -0.0207726142 |
| PubMed_21979375_A1 | Down | -0.8342950885 |
| PubMed_21979375_A2 | Down | -0.5001782986 |
| GSE35957 | Down | -0.1502725206 |
| GSE36640 | Up | 0.1324973903 |
| GSE54402 | Down | -0.6297470173 |
| GSE9593 | Down | -0.1023851161 |
| GSE43922 | Up | 0.0109616172 |
| GSE24585 | Up | 0.3356193786 |
| GSE37065 | Down | -0.1380801009 |
| GSE28863_A1 | Up | 0.0356794847 |
| GSE28863_A2 | Down | -0.3076285156 |
| GSE28863_A3 | Down | -0.6070442803 |
| GSE28863_A4 | Down | -0.0386308481 |
| GSE48662 | Up | 0.0158480950 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022133 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027420 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041522 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
