HCSGD entry for CDK17
1. General information
| Official gene symbol | CDK17 |
|---|---|
| Entrez ID | 5128 |
| Gene full name | cyclin-dependent kinase 17 |
| Other gene symbols | PCTAIRE2 PCTK2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0046053607 | 0.5943534554 | 0.1785238586 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5915033024 |
| GSE13712_SHEAR | Down | -0.0679767751 |
| GSE13712_STATIC | Down | -0.4642899332 |
| GSE19018 | Down | -0.4114287851 |
| GSE19899_A1 | Up | 1.5549648625 |
| GSE19899_A2 | Up | 1.2576591086 |
| PubMed_21979375_A1 | Up | 2.4904131135 |
| PubMed_21979375_A2 | Up | 2.0602674656 |
| GSE35957 | Down | -0.2560784811 |
| GSE36640 | Down | -0.4404420253 |
| GSE54402 | Up | 1.1892636910 |
| GSE9593 | Down | -0.0402913249 |
| GSE43922 | Up | 1.3467125772 |
| GSE24585 | Up | 0.0630802430 |
| GSE37065 | Up | 0.0542524100 |
| GSE28863_A1 | Down | -0.0690176523 |
| GSE28863_A2 | Up | 0.2544717330 |
| GSE28863_A3 | Down | -0.5292724694 |
| GSE28863_A4 | Up | 0.1293519060 |
| GSE48662 | Down | -0.1751191591 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017391 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027115 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027559 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031589 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041319 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
