HCSGD entry for CDK16
1. General information
| Official gene symbol | CDK16 |
|---|---|
| Entrez ID | 5127 |
| Gene full name | cyclin-dependent kinase 16 |
| Other gene symbols | PCTAIRE PCTAIRE1 PCTGAIRE PCTK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0006887 | Exocytosis | IEA ISS | biological_process |
| GO:0007283 | Spermatogenesis | IEA ISS | biological_process |
| GO:0008021 | Synaptic vesicle | IEA ISS | cellular_component |
| GO:0016772 | Transferase activity, transferring phosphorus-containing groups | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030133 | Transport vesicle | IEA | cellular_component |
| GO:0030252 | Growth hormone secretion | IEA ISS | biological_process |
| GO:0031175 | Neuron projection development | IEA ISS | biological_process |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IDA | cellular_component |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0061178 | Regulation of insulin secretion involved in cellular response to glucose stimulus | IEA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6015500627 | 0.0951956233 | 0.9999902473 | 0.5880413049 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0392274849 |
| GSE13712_SHEAR | Down | -0.2591580211 |
| GSE13712_STATIC | Down | -0.1039704461 |
| GSE19018 | Up | 0.2600908062 |
| GSE19899_A1 | Down | -0.1350525905 |
| GSE19899_A2 | Up | 0.2872508070 |
| PubMed_21979375_A1 | Up | 1.1583802400 |
| PubMed_21979375_A2 | Up | 1.2021015586 |
| GSE35957 | Down | -0.6460295560 |
| GSE36640 | Down | -0.3691915177 |
| GSE54402 | Down | -0.0142776702 |
| GSE9593 | Down | -0.2492339408 |
| GSE43922 | Down | -0.0638104502 |
| GSE24585 | Down | -0.7199767324 |
| GSE37065 | Down | -0.1936771173 |
| GSE28863_A1 | Down | -0.1207787835 |
| GSE28863_A2 | Up | 0.1122029868 |
| GSE28863_A3 | Down | -0.5822585845 |
| GSE28863_A4 | Up | 0.0381413614 |
| GSE48662 | Up | 0.1417040846 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} | DB07766 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037393 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050576 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
