HCSGD entry for CDKL3


1. General information

Official gene symbolCDKL3
Entrez ID51265
Gene full namecyclin-dependent kinase-like 3
Other gene symbolsNKIAMRE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004672Protein kinase activityIEA TASmolecular_function
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004693Cyclin-dependent protein serine/threonine kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0006464Cellular protein modification processTASbiological_process
GO:0016301Kinase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06211976370.98443803430.53912191831.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2474641267
GSE13712_SHEARUp0.0743819374
GSE13712_STATICDown-0.1801733106
GSE19018Up0.1411001217
GSE19899_A1Up0.1789033255
GSE19899_A2Up0.1903306448
PubMed_21979375_A1Up0.1793650143
PubMed_21979375_A2Up0.5542396307
GSE35957Up0.0274509131
GSE36640Up0.6169551967
GSE54402Up0.0622712280
GSE9593Up0.0577357435
GSE43922Up0.2142155689
GSE24585Up0.2627033010
GSE37065Up0.2398477875
GSE28863_A1Down-0.0773253480
GSE28863_A2Up0.2735489109
GSE28863_A3Down-0.0584029473
GSE28863_A4Up0.0964862843
GSE48662Up0.2432463709

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.