HCSGD entry for CRIM1


1. General information

Official gene symbolCRIM1
Entrez ID51232
Gene full namecysteine rich transmembrane BMP regulator 1 (chordin-like)
Other gene symbolsCRIM-1 S52
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthIEAbiological_process
GO:0004867Serine-type endopeptidase inhibitor activityIEAmolecular_function
GO:0005010Insulin-like growth factor-activated receptor activityTASmolecular_function
GO:0005520Insulin-like growth factor bindingIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016310PhosphorylationTASbiological_process
GO:0018108Peptidyl-tyrosine phosphorylationTASbiological_process
GO:0030165PDZ domain bindingIDAmolecular_function
GO:0048009Insulin-like growth factor receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87283043960.00308639110.99999024730.1114360768

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.1806192073
GSE13712_SHEARUp0.3750168730
GSE13712_STATICUp0.1466753699
GSE19018Up0.4916320495
GSE19899_A1Down-1.7132076799
GSE19899_A2Down-0.8170392116
PubMed_21979375_A1Down-1.8010156969
PubMed_21979375_A2Down-1.5803020951
GSE35957Up0.4095993593
GSE36640Up0.4472319135
GSE54402Down-0.7402694905
GSE9593Up0.5126576279
GSE43922Down-1.0536341466
GSE24585Down-0.5179185857
GSE37065Down-0.4916578975
GSE28863_A1Down-0.1477463841
GSE28863_A2Down-0.0934285425
GSE28863_A3Down-0.3203285382
GSE28863_A4Down-0.1189029403
GSE48662Down-0.1760643486

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-20b-5pMIMAT0001413MIRT004053Luciferase reporter assay//qRT-PCRFunctional MTI21042576
hsa-miR-375MIMAT0000728MIRT020040MicroarrayFunctional MTI (Weak)20215506
hsa-miR-26b-5pMIMAT0000083MIRT030160MicroarrayFunctional MTI (Weak)19088304
hsa-miR-455-3pMIMAT0004784MIRT037869CLASHFunctional MTI (Weak)23622248
hsa-miR-92b-3pMIMAT0003218MIRT040735CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.