HCSGD entry for GLRX5
1. General information
| Official gene symbol | GLRX5 |
|---|---|
| Entrez ID | 51218 |
| Gene full name | glutaredoxin 5 |
| Other gene symbols | C14orf87 FLB4739 GRX5 PR01238 PRO1238 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA ISS | cellular_component |
| GO:0009055 | Electron carrier activity | IEA | molecular_function |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0030097 | Hemopoiesis | ISS | biological_process |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051537 | 2 iron, 2 sulfur cluster binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9110267885 | 0.0963865887 | 0.9999902473 | 0.5918739039 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2665891165 |
| GSE13712_SHEAR | Down | -0.1864184987 |
| GSE13712_STATIC | Down | -0.1293556422 |
| GSE19018 | Up | 0.2289361912 |
| GSE19899_A1 | Down | -0.5930527842 |
| GSE19899_A2 | Up | 0.6825540445 |
| PubMed_21979375_A1 | Down | -1.3127746942 |
| PubMed_21979375_A2 | Up | 0.0419644631 |
| GSE35957 | Down | -0.2921838906 |
| GSE36640 | Down | -0.5166202377 |
| GSE54402 | Up | 0.0196098167 |
| GSE9593 | Down | -0.0917084722 |
| GSE43922 | Down | -0.0437906759 |
| GSE24585 | Down | -0.1627260847 |
| GSE37065 | Down | -0.2058758706 |
| GSE28863_A1 | Down | -0.1203545346 |
| GSE28863_A2 | Down | -0.2852443622 |
| GSE28863_A3 | Up | 0.1084368001 |
| GSE28863_A4 | Up | 0.1375130993 |
| GSE48662 | Down | -0.1744316913 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-222-3p | MIMAT0000279 | MIRT046660 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050727 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23634235 | Amongst the genes were IRAK3, SelS, HSPA5, HERPUD1, DNAJB9, SEPR1, C18orf55, ARF4, RINT1, NXT1, CADPS2, COG6, and GLRX5 |
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