HCSGD entry for RAPGEFL1
1. General information
| Official gene symbol | RAPGEFL1 |
|---|---|
| Entrez ID | 51195 |
| Gene full name | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| Other gene symbols | Link-GEFII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005057 | Receptor signaling protein activity | IEA | molecular_function |
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0043087 | Regulation of GTPase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8821991338 | 0.5023410395 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2049876823 |
| GSE13712_SHEAR | Down | -0.0375425479 |
| GSE13712_STATIC | Up | 0.0005945998 |
| GSE19018 | Up | 0.1220302482 |
| GSE19899_A1 | Down | -0.0182203296 |
| GSE19899_A2 | Up | 0.0168936182 |
| PubMed_21979375_A1 | Down | -0.4025820837 |
| PubMed_21979375_A2 | Up | 0.0095464245 |
| GSE35957 | Up | 0.0294102865 |
| GSE36640 | Up | 0.0837043748 |
| GSE54402 | Up | 0.0309300039 |
| GSE9593 | Down | -0.0558740728 |
| GSE43922 | Down | -0.1219245522 |
| GSE24585 | Down | -0.0332727706 |
| GSE37065 | Up | 0.1252355002 |
| GSE28863_A1 | Up | 0.0437375274 |
| GSE28863_A2 | Up | 0.0434756780 |
| GSE28863_A3 | Up | 0.1225897849 |
| GSE28863_A4 | Down | -0.0736631527 |
| GSE48662 | Down | -0.0185789522 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-296-3p | MIMAT0004679 | MIRT038353 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047947 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051841 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
