HCSGD entry for DCXR
1. General information
| Official gene symbol | DCXR |
|---|---|
| Entrez ID | 51181 |
| Gene full name | dicarbonyl/L-xylulose reductase |
| Other gene symbols | DCR HCR2 HCRII KIDCR P34H SDR20C1 XR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005881 | Cytoplasmic microtubule | IDA | cellular_component |
| GO:0005902 | Microvillus | IEA | cellular_component |
| GO:0005903 | Brush border | IEA | cellular_component |
| GO:0005997 | Xylulose metabolic process | IDA | biological_process |
| GO:0006006 | Glucose metabolic process | IDA | biological_process |
| GO:0006739 | NADP metabolic process | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0016655 | Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | IDA | molecular_function |
| GO:0042732 | D-xylose metabolic process | IEA | biological_process |
| GO:0050038 | L-xylulose reductase (NADP+) activity | IDA | molecular_function |
| GO:0051289 | Protein homotetramerization | IDA | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2706251776 | 0.0385355610 | 0.9680564325 | 0.3696408528 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5190681605 |
| GSE13712_SHEAR | Up | 0.3635151848 |
| GSE13712_STATIC | Up | 0.3760524218 |
| GSE19018 | Up | 0.2781805695 |
| GSE19899_A1 | Down | -1.6936112366 |
| GSE19899_A2 | Down | -0.3909572713 |
| PubMed_21979375_A1 | Up | 0.1149219440 |
| PubMed_21979375_A2 | Down | -0.8388013391 |
| GSE35957 | Down | -1.0574133220 |
| GSE36640 | Down | -0.0497531311 |
| GSE54402 | Up | 0.0591676125 |
| GSE9593 | Down | -0.5788560912 |
| GSE43922 | Down | -0.5353016781 |
| GSE24585 | Up | 1.0308144332 |
| GSE37065 | Down | -0.0893318775 |
| GSE28863_A1 | Down | -0.5186748879 |
| GSE28863_A2 | Down | -0.3144329818 |
| GSE28863_A3 | Down | -0.0978519083 |
| GSE28863_A4 | Up | 0.0590194710 |
| GSE48662 | Up | 0.2836133447 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Isopropyl Alcohol | DB02325 | EXPT01912 | DB04402 |
| Dihydrogenphosphate Ion | DB02831 | EXPT00124 |
| 2'-Monophosphoadenosine 5'-Diphosphoribose | DB03461 | EXPT02293 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-744-5p | MIMAT0004945 | MIRT037386 | CLASH | Functional MTI (Weak) | 23622248 |
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