HCSGD entry for HSD17B14
1. General information
| Official gene symbol | HSD17B14 |
|---|---|
| Entrez ID | 51171 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 14 |
| Other gene symbols | DHRS10 SDR47C1 retSDR3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004303 | Estradiol 17-beta-dehydrogenase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006706 | Steroid catabolic process | IDA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0047045 | Testosterone 17-beta-dehydrogenase (NADP+) activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2453902435 | 0.0530785305 | 0.9344497396 | 0.4344052795 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0605965744 |
| GSE13712_SHEAR | Down | -0.9202977680 |
| GSE13712_STATIC | Down | -0.4177024764 |
| GSE19018 | Up | 0.2198337866 |
| GSE19899_A1 | Down | -0.2403642105 |
| GSE19899_A2 | Up | 0.4245685632 |
| PubMed_21979375_A1 | Down | -0.5379291701 |
| PubMed_21979375_A2 | Up | 0.1555481891 |
| GSE35957 | Down | -0.0092743884 |
| GSE36640 | Up | 0.4002223377 |
| GSE54402 | Up | 0.2090258344 |
| GSE9593 | Up | 0.1027807988 |
| GSE43922 | Down | -0.0585652064 |
| GSE24585 | Up | 0.8278816513 |
| GSE37065 | Down | -0.0254712881 |
| GSE28863_A1 | Down | -1.4578430159 |
| GSE28863_A2 | Down | -0.3848445479 |
| GSE28863_A3 | Down | -0.7139306771 |
| GSE28863_A4 | Up | 0.2338501977 |
| GSE48662 | Up | 0.6363579837 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030036 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
