HCSGD entry for DCTN4
1. General information
| Official gene symbol | DCTN4 |
|---|---|
| Entrez ID | 51164 |
| Gene full name | dynactin 4 (p62) |
| Other gene symbols | DYN4 P62 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005869 | Dynactin complex | IEA | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0605415144 | 0.8182998860 | 0.5330699097 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2910023064 |
| GSE13712_SHEAR | Up | 0.2266992210 |
| GSE13712_STATIC | Up | 0.1413702935 |
| GSE19018 | Down | -0.0140148951 |
| GSE19899_A1 | Up | 0.3655347713 |
| GSE19899_A2 | Up | 0.2432000882 |
| PubMed_21979375_A1 | Up | 0.7076588053 |
| PubMed_21979375_A2 | Up | 0.4449991920 |
| GSE35957 | Up | 0.1970995738 |
| GSE36640 | Up | 0.7935667105 |
| GSE54402 | Up | 0.3910175075 |
| GSE9593 | Up | 0.2851559230 |
| GSE43922 | Up | 0.2617313532 |
| GSE24585 | Up | 0.0271048277 |
| GSE37065 | Up | 0.0681900180 |
| GSE28863_A1 | Down | -0.1551293240 |
| GSE28863_A2 | Up | 0.1127843514 |
| GSE28863_A3 | Down | -0.7662601017 |
| GSE28863_A4 | Down | -0.4138127927 |
| GSE48662 | Down | -0.2474127063 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-142-3p | MIMAT0000434 | MIRT021605 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028163 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-484 | MIMAT0002174 | MIRT042076 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043893 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045463 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
