HCSGD entry for DBR1


1. General information

Official gene symbolDBR1
Entrez ID51163
Gene full namedebranching RNA lariats 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000375RNA splicing, via transesterification reactionsIMPbiological_process
GO:0000398MRNA splicing, via spliceosomeIEAbiological_process
GO:0005634NucleusIDAcellular_component
GO:0008419RNA lariat debranching enzyme activityIMPmolecular_function
GO:0016787Hydrolase activityIEAmolecular_function
GO:0016788Hydrolase activity, acting on ester bondsIEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:0090305Nucleic acid phosphodiester bond hydrolysisIMPbiological_process
GO:0090501RNA phosphodiester bond hydrolysisIMPbiological_process
GO:0090502RNA phosphodiester bond hydrolysis, endonucleolyticIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91196964400.06374394210.99999024730.4759728511

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2910320271
GSE13712_SHEARUp0.0964275377
GSE13712_STATICUp0.4460824932
GSE19018Down-0.5484647230
GSE19899_A1Down-0.3792024759
GSE19899_A2Down-0.1194259227
PubMed_21979375_A1Down-0.0060448291
PubMed_21979375_A2Down-0.3210568673
GSE35957Up0.0330265249
GSE36640Down-0.6180284691
GSE54402Down-0.1875641625
GSE9593Down-0.1783991847
GSE43922Down-0.0354569127
GSE24585Up0.2385576561
GSE37065Up0.1270301683
GSE28863_A1Up0.0795731533
GSE28863_A2Up0.4211119770
GSE28863_A3Down-0.5420750818
GSE28863_A4Down-0.2810219048
GSE48662Down-0.1368836107

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-3pMIMAT0004504MIRT038937CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.