HCSGD entry for SUV420H1
1. General information
| Official gene symbol | SUV420H1 |
|---|---|
| Entrez ID | 51111 |
| Gene full name | suppressor of variegation 4-20 homolog 1 (Drosophila) |
| Other gene symbols | CGI85 KMT5B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000780 | Condensed nuclear chromosome, centromeric region | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0018024 | Histone-lysine N-methyltransferase activity | IDA | molecular_function |
| GO:0034773 | Histone H4-K20 trimethylation | IEA | biological_process |
| GO:0042799 | Histone methyltransferase activity (H4-K20 specific) | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5166511721 | 0.2715896508 | 0.9999902473 | 0.9968061062 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5829685942 |
| GSE13712_SHEAR | Down | -0.2056945663 |
| GSE13712_STATIC | Down | -0.2140723453 |
| GSE19018 | Down | -0.3830901007 |
| GSE19899_A1 | Up | 0.0740715014 |
| GSE19899_A2 | Up | 0.0712298816 |
| PubMed_21979375_A1 | Up | 0.8112407777 |
| PubMed_21979375_A2 | Up | 0.4357811086 |
| GSE35957 | Down | -0.1563077922 |
| GSE36640 | Down | -0.1166132659 |
| GSE54402 | Down | -0.0185891899 |
| GSE9593 | Down | -0.3372250612 |
| GSE43922 | Down | -0.0211437278 |
| GSE24585 | Up | 0.4558855883 |
| GSE37065 | Up | 0.0837383695 |
| GSE28863_A1 | Up | 0.4711053381 |
| GSE28863_A2 | Up | 0.1641051263 |
| GSE28863_A3 | Down | -0.1121933884 |
| GSE28863_A4 | Down | -0.0312967661 |
| GSE48662 | Down | -0.1849774807 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016220 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020188 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028080 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028330 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028707 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031143 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-3p | MIMAT0004494 | MIRT038965 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT045876 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
