HCSGD entry for RDH11
1. General information
| Official gene symbol | RDH11 |
|---|---|
| Entrez ID | 51109 |
| Gene full name | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| Other gene symbols | ARSDR1 CGI82 HCBP12 MDT1 PSDR1 RALR1 SCALD SDR7C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001523 | Retinoid metabolic process | TAS | biological_process |
| GO:0001917 | Photoreceptor inner segment | IEA | cellular_component |
| GO:0004745 | Retinol dehydrogenase activity | ISS | molecular_function |
| GO:0005622 | Intracellular | ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0007603 | Phototransduction, visible light | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016062 | Adaptation of rhodopsin mediated signaling | IEA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0042572 | Retinol metabolic process | ISS | biological_process |
| GO:0042574 | Retinal metabolic process | IDA | biological_process |
| GO:0052650 | NADP-retinol dehydrogenase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3560230500 | 0.7446855895 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1974517978 |
| GSE13712_SHEAR | Up | 0.0750718246 |
| GSE13712_STATIC | Down | -0.1429968012 |
| GSE19018 | Up | 0.1947883431 |
| GSE19899_A1 | Up | 0.1536064036 |
| GSE19899_A2 | Up | 0.3112168350 |
| PubMed_21979375_A1 | Down | -0.3917897252 |
| PubMed_21979375_A2 | Up | 0.0306381390 |
| GSE35957 | Down | -0.1266389419 |
| GSE36640 | Up | 0.2228108261 |
| GSE54402 | Up | 0.0373179555 |
| GSE9593 | Down | -0.0797326376 |
| GSE43922 | Up | 0.1588502517 |
| GSE24585 | Down | -0.0031057478 |
| GSE37065 | Up | 0.1715821902 |
| GSE28863_A1 | Down | -0.0475676383 |
| GSE28863_A2 | Up | 0.3677570211 |
| GSE28863_A3 | Down | -0.6497686894 |
| GSE28863_A4 | Up | 0.0899132091 |
| GSE48662 | Down | -0.2345185620 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin A | DB00162 | NUTR00007 | APRD00486 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016191 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-375 | MIMAT0000728 | MIRT020023 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020293 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025299 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025299 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031076 | Microarray | Functional MTI (Weak) | 17363372 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031076 | Microarray | Functional MTI (Weak) | 19342589 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031076 | Microarray | Functional MTI (Weak) | 18270520 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031076 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031213 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047120 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048185 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048351 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
