HCSGD entry for MECR
1. General information
| Official gene symbol | MECR |
|---|---|
| Entrez ID | 51102 |
| Gene full name | mitochondrial trans-2-enoyl-CoA reductase |
| Other gene symbols | CGI-63 FASN2B NRBF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006631 | Fatty acid metabolic process | IDA | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0019166 | Trans-2-enoyl-CoA reductase (NADPH) activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9485112192 | 0.1132727100 | 0.9999902473 | 0.6450564691 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3248386766 |
| GSE13712_SHEAR | Down | -0.2104409600 |
| GSE13712_STATIC | Down | -0.0819433122 |
| GSE19018 | Down | -0.2524389656 |
| GSE19899_A1 | Down | -0.2906364721 |
| GSE19899_A2 | Up | 0.3691844482 |
| PubMed_21979375_A1 | Up | 0.3843483483 |
| PubMed_21979375_A2 | Down | -0.0234403656 |
| GSE35957 | Down | -0.1993907045 |
| GSE36640 | Down | -0.2739666545 |
| GSE54402 | Up | 0.1405362004 |
| GSE9593 | Down | -0.4081197066 |
| GSE43922 | Up | 0.0389984222 |
| GSE24585 | Down | -0.1036634866 |
| GSE37065 | Down | -0.0428514352 |
| GSE28863_A1 | Down | -0.0128688109 |
| GSE28863_A2 | Down | -0.0155872475 |
| GSE28863_A3 | Down | -0.2207228226 |
| GSE28863_A4 | Down | -0.2235747726 |
| GSE48662 | Up | 0.0177119632 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020488 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023488 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7f-1-3p | MIMAT0004486 | MIRT038990 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043378 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
